Assessment of histopatoligical changes of liver of Aphanius sophiae by Cadmium and Arsenic

In this study was investigated histipathological effects of Cd and As on liver of Aphanius sophiae. For this reason, 350 specimens were collected on 2011 from the Shoor River. For saltwater and separately freshwater treatment were designed seven treatments including the concentrations of 5, 10 and 20 for As 5, 10 and 20 for Cd and a control treatment in 30- L aquaria with three replicates. Twenty five specimens were introduced into each aquarium. After 18 days of exposure, three specimens were sampled from each treatment and fixed into Bouin solution and their liver were removed for histological preparation. The results showed that increasing the Cd and As concentrations in salt treatment increased hepatocyte necrosis and atrophy. The results in freshwater showed that with increasing concentrations cloudy swelling and atrophy were observed. The results indicated that the tissue destruction in As treatment more higher than in Cd, also, in freshwater was higher than in salt water. The losses rate of 11/4 time in fresh water confirmed these results.